Magnesium

Role of Magnesium (Mg) in the Body

Magnesium is a vital mineral involved in more than 300 biochemical reactions. It is essential for the nervous system, muscles, heart, bones, and metabolism.

Main functions of magnesium:

  1. Energy metabolism – participates in ATP synthesis (the main energy source).
  2. Neuromuscular regulation – controls nerve impulse transmission and muscle contraction (including the heart).
  3. Cardiovascular system – supports heart rhythm, lowers blood pressure.
  4. Bone tissue – strengthens bones (60% of magnesium is stored in the skeleton).
  5. DNA and protein synthesis – necessary for cell division and enzyme production.
  6. Blood glucose regulation – affects insulin action.

Symptoms of Magnesium Deficiency (Hypomagnesemia)

Magnesium deficiency is common, especially with unbalanced nutrition, stress, or gastrointestinal diseases.

Early signs:

  • Muscle cramps (especially at night)
  • Eye twitching, tremor
  • Fatigue, irritability, insomnia
  • Headaches, dizziness

Severe deficiency:

  • Arrhythmia (extrasystole, tachycardia)
  • Numbness and tingling in extremities
  • Seizures (tetany)
  • Depression, anxiety
  • Increased blood pressure

Risk groups:

  • People with gastrointestinal diseases (celiac disease, Crohn’s disease)
  • Diabetics (insulin resistance increases Mg loss)
  • Alcoholics (ethanol excretes magnesium)
  • Pregnant women and athletes (increased consumption)
  • Taking diuretics (furosemide) or proton pump inhibitors (omeprazole)

Symptoms of Magnesium Excess (Hypermagnesemia)

Magnesium overdose is rare and usually occurs with kidney failure or excessive supplement intake.

Signs of excess:

  • Nausea, vomiting, diarrhea
  • Weakness, drowsiness
  • Low blood pressure
  • Slow pulse (bradycardia)
  • Respiratory distress (in severe cases – coma)

Dangerous levels (> 2.5 mmol/L):

  • CNS depression
  • Cardiac arrest (with sharp increase)

Normal Magnesium Levels in Blood

Magnesium levels are determined in blood serum. Reference values:

  • Adults: 0.7–1.1 mmol/L (≈ 1.7–2.6 mg/dL)
  • Children: 0.6–1.0 mmol/L

Notes:

  • Blood magnesium test does not always reflect total deficiency, as 99% of Mg is inside cells and bones.
  • For accurate diagnosis, erythrocyte magnesium or 24-hour urine magnesium excretion is sometimes checked.

How to Maintain Magnesium Levels?

Sources of magnesium:

  • Nuts (almonds, cashews)
  • Seeds (pumpkin, sunflower)
  • Green leafy vegetables (spinach)
  • Legumes (beans, lentils)
  • Dark chocolate (>70% cocoa)

Supplements (as prescribed by a doctor):

  • Magnesium citrate (best absorption)
  • Magnesium glycinate (gentle action, suitable for stress)

Important! In case of kidney failure, magnesium intake should be supervised by a doctor.


Conclusion

Magnesium is a key mineral for the heart, nerves, and muscles. Deficiency manifests as cramps, arrhythmia, and fatigue, while excess (rarely) causes weakness and bradycardia. Normal blood level: 0.7–1.1 mmol/L. For prevention, include nuts, greens, and legumes in your diet.